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Contraindicated (1)pentobarbital decreases amounts of vandetanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay clear of coadministration with strong CYP3A4 inducers; these medication reduce exposure to vandetanib by nearly forty%.fentanyl iontophoretic transdermal program and pentobarbital both raise sedation. Avoi

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